Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19).
Identifieur interne : 000220 ( new/Analysis ); précédent : 000219; suivant : 000221Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19).
Auteurs : Li Guo [République populaire de Chine] ; Lili Ren [République populaire de Chine] ; Siyuan Yang [République populaire de Chine] ; Meng Xiao [République populaire de Chine] ; De Chang [République populaire de Chine] ; Fan Yang ; Charles S. Dela Cruz [États-Unis] ; Yingying Wang [République populaire de Chine] ; Chao Wu [République populaire de Chine] ; Yan Xiao [République populaire de Chine] ; Lulu Zhang [République populaire de Chine] ; Lianlian Han [République populaire de Chine] ; Shengyuan Dang [République populaire de Chine] ; Yan Xu [République populaire de Chine] ; Qiwen Yang [République populaire de Chine] ; Shengyong Xu [République populaire de Chine] ; Huadong Zhu [République populaire de Chine] ; Yingchun Xu [République populaire de Chine] ; Qi Jin ; Lokesh Sharma [États-Unis] ; Linghang Wang [République populaire de Chine] ; Jianwei Wang [République populaire de Chine]Source :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2020.
Abstract
Emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. Current method of detection involves qPCR-based technique, which identifies the viral nucleic acids when present in sufficient quantity. False negative results can be achieved and failure to quarantine the infected patient would be a major setback in containing the viral transmission. We here aim to describe the time kinetics of various antibodies produced against the 2019 novel coronavirus (SARS-CoV-2) and evaluate the potential of antibody testing to diagnose COVID-19.
DOI: 10.1093/cid/ciaa310
PubMed: 32198501
Affiliations:
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China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xiao, Yan" sort="Xiao, Yan" uniqKey="Xiao Y" first="Yan" last="Xiao">Yan Xiao</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. 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China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xu, Yan" sort="Xu, Yan" uniqKey="Xu Y" first="Yan" last="Xu">Yan Xu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. 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China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xu, Shengyong" sort="Xu, Shengyong" uniqKey="Xu S" first="Shengyong" last="Xu">Shengyong Xu</name><affiliation wicri:level="3"><nlm:affiliation>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhu, Huadong" sort="Zhu, Huadong" uniqKey="Zhu H" first="Huadong" last="Zhu">Huadong Zhu</name><affiliation wicri:level="3"><nlm:affiliation>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xu, Yingchun" sort="Xu, Yingchun" uniqKey="Xu Y" first="Yingchun" last="Xu">Yingchun Xu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Jin, Qi" sort="Jin, Qi" uniqKey="Jin Q" first="Qi" last="Jin">Qi Jin</name><affiliation><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing P. R. China.</nlm:affiliation><wicri:noCountry code="subField">Beijing P</wicri:noCountry></affiliation></author><author><name sortKey="Sharma, Lokesh" sort="Sharma, Lokesh" uniqKey="Sharma L" first="Lokesh" last="Sharma">Lokesh Sharma</name><affiliation wicri:level="2"><nlm:affiliation>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT USA.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Linghang" sort="Wang, Linghang" uniqKey="Wang L" first="Linghang" last="Wang">Linghang Wang</name><affiliation wicri:level="3"><nlm:affiliation>Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Jianwei" sort="Wang, Jianwei" uniqKey="Wang J" first="Jianwei" last="Wang">Jianwei Wang</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32198501</idno><idno type="pmid">32198501</idno><idno type="doi">10.1093/cid/ciaa310</idno><idno type="wicri:Area/PubMed/Corpus">000184</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000184</idno><idno type="wicri:Area/PubMed/Curation">000184</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000184</idno><idno type="wicri:Area/PubMed/Checkpoint">000412</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000412</idno><idno type="wicri:Area/Ncbi/Merge">001420</idno><idno type="wicri:Area/Ncbi/Curation">001420</idno><idno type="wicri:Area/Ncbi/Checkpoint">001420</idno><idno type="wicri:Area/Main/Merge">000449</idno><idno type="wicri:Area/Main/Curation">000447</idno><idno type="wicri:Area/Main/Exploration">000447</idno><idno type="wicri:Area/new/Extraction">000220</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19).</title><author><name sortKey="Guo, Li" sort="Guo, Li" uniqKey="Guo L" first="Li" last="Guo">Li Guo</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Ren, Lili" sort="Ren, Lili" uniqKey="Ren L" first="Lili" last="Ren">Lili Ren</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yang, Siyuan" sort="Yang, Siyuan" uniqKey="Yang S" first="Siyuan" last="Yang">Siyuan Yang</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Infectious Diseases Center of Beijing Ditan Hospital, Capital Medical University, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Laboratory of Infectious Diseases Center of Beijing Ditan Hospital, Capital Medical University</wicri:regionArea><wicri:noRegion>Capital Medical University</wicri:noRegion></affiliation></author><author><name sortKey="Xiao, Meng" sort="Xiao, Meng" uniqKey="Xiao M" first="Meng" last="Xiao">Meng Xiao</name><affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Chang, De" sort="Chang, De" uniqKey="Chang D" first="De" last="Chang">De Chang</name><affiliation wicri:level="3"><nlm:affiliation>Third Medical Center of Chinese PLA General Hospital, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Third Medical Center of Chinese PLA General Hospital, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yang, Fan" sort="Yang, Fan" uniqKey="Yang F" first="Fan" last="Yang">Fan Yang</name><affiliation><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing P. R. China.</nlm:affiliation><wicri:noCountry code="subField">Beijing P</wicri:noCountry></affiliation></author><author><name sortKey="Dela Cruz, Charles S" sort="Dela Cruz, Charles S" uniqKey="Dela Cruz C" first="Charles S" last="Dela Cruz">Charles S. Dela Cruz</name><affiliation wicri:level="2"><nlm:affiliation>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT USA.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Yingying" sort="Wang, Yingying" uniqKey="Wang Y" first="Yingying" last="Wang">Yingying Wang</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wu, Chao" sort="Wu, Chao" uniqKey="Wu C" first="Chao" last="Wu">Chao Wu</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xiao, Yan" sort="Xiao, Yan" uniqKey="Xiao Y" first="Yan" last="Xiao">Yan Xiao</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Lulu" sort="Zhang, Lulu" uniqKey="Zhang L" first="Lulu" last="Zhang">Lulu Zhang</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Han, Lianlian" sort="Han, Lianlian" uniqKey="Han L" first="Lianlian" last="Han">Lianlian Han</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Dang, Shengyuan" sort="Dang, Shengyuan" uniqKey="Dang S" first="Shengyuan" last="Dang">Shengyuan Dang</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xu, Yan" sort="Xu, Yan" uniqKey="Xu Y" first="Yan" last="Xu">Yan Xu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yang, Qiwen" sort="Yang, Qiwen" uniqKey="Yang Q" first="Qiwen" last="Yang">Qiwen Yang</name><affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xu, Shengyong" sort="Xu, Shengyong" uniqKey="Xu S" first="Shengyong" last="Xu">Shengyong Xu</name><affiliation wicri:level="3"><nlm:affiliation>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhu, Huadong" sort="Zhu, Huadong" uniqKey="Zhu H" first="Huadong" last="Zhu">Huadong Zhu</name><affiliation wicri:level="3"><nlm:affiliation>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xu, Yingchun" sort="Xu, Yingchun" uniqKey="Xu Y" first="Yingchun" last="Xu">Yingchun Xu</name><affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Department of Laboratory Medicine & Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Jin, Qi" sort="Jin, Qi" uniqKey="Jin Q" first="Qi" last="Jin">Qi Jin</name><affiliation><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing P. R. China.</nlm:affiliation><wicri:noCountry code="subField">Beijing P</wicri:noCountry></affiliation></author><author><name sortKey="Sharma, Lokesh" sort="Sharma, Lokesh" uniqKey="Sharma L" first="Lokesh" last="Sharma">Lokesh Sharma</name><affiliation wicri:level="2"><nlm:affiliation>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT USA.</nlm:affiliation><country>États-Unis</country><placeName><region type="state">Connecticut</region></placeName><wicri:cityArea>Section of Pulmonary and Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven</wicri:cityArea></affiliation></author><author><name sortKey="Wang, Linghang" sort="Wang, Linghang" uniqKey="Wang L" first="Linghang" last="Wang">Linghang Wang</name><affiliation wicri:level="3"><nlm:affiliation>Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Emergency Department of Infectious Diseases of Beijing Ditan Hospital, Capital Medical University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Jianwei" sort="Wang, Jianwei" uniqKey="Wang J" first="Jianwei" last="Wang">Jianwei Wang</name><affiliation wicri:level="3"><nlm:affiliation>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing, P. R. China.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux, Institute of Pathogen Biology (IPB), Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="eISSN">1537-6591</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. Current method of detection involves qPCR-based technique, which identifies the viral nucleic acids when present in sufficient quantity. False negative results can be achieved and failure to quarantine the infected patient would be a major setback in containing the viral transmission. We here aim to describe the time kinetics of various antibodies produced against the 2019 novel coronavirus (SARS-CoV-2) and evaluate the potential of antibody testing to diagnose COVID-19.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Connecticut</li></region><settlement><li>Pékin</li></settlement></list><tree><noCountry><name sortKey="Jin, Qi" sort="Jin, Qi" uniqKey="Jin Q" first="Qi" last="Jin">Qi Jin</name><name sortKey="Yang, Fan" sort="Yang, Fan" uniqKey="Yang F" first="Fan" last="Yang">Fan Yang</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Guo, Li" sort="Guo, Li" uniqKey="Guo L" first="Li" last="Guo">Li Guo</name></noRegion><name sortKey="Chang, De" sort="Chang, De" uniqKey="Chang D" first="De" last="Chang">De Chang</name><name sortKey="Dang, Shengyuan" sort="Dang, Shengyuan" uniqKey="Dang S" first="Shengyuan" last="Dang">Shengyuan Dang</name><name sortKey="Han, Lianlian" sort="Han, Lianlian" uniqKey="Han L" first="Lianlian" last="Han">Lianlian Han</name><name sortKey="Ren, Lili" sort="Ren, Lili" uniqKey="Ren L" first="Lili" last="Ren">Lili Ren</name><name sortKey="Wang, Jianwei" sort="Wang, Jianwei" uniqKey="Wang J" first="Jianwei" last="Wang">Jianwei Wang</name><name sortKey="Wang, Linghang" sort="Wang, Linghang" uniqKey="Wang L" first="Linghang" last="Wang">Linghang Wang</name><name sortKey="Wang, Yingying" sort="Wang, Yingying" uniqKey="Wang Y" first="Yingying" last="Wang">Yingying Wang</name><name sortKey="Wu, Chao" sort="Wu, Chao" uniqKey="Wu C" first="Chao" last="Wu">Chao Wu</name><name sortKey="Xiao, Meng" sort="Xiao, Meng" uniqKey="Xiao M" first="Meng" last="Xiao">Meng Xiao</name><name sortKey="Xiao, Yan" sort="Xiao, Yan" uniqKey="Xiao Y" first="Yan" last="Xiao">Yan Xiao</name><name sortKey="Xu, Shengyong" sort="Xu, Shengyong" uniqKey="Xu S" first="Shengyong" last="Xu">Shengyong Xu</name><name sortKey="Xu, Yan" sort="Xu, Yan" uniqKey="Xu Y" first="Yan" last="Xu">Yan Xu</name><name sortKey="Xu, Yingchun" sort="Xu, Yingchun" uniqKey="Xu Y" first="Yingchun" last="Xu">Yingchun Xu</name><name sortKey="Yang, Qiwen" sort="Yang, Qiwen" uniqKey="Yang Q" first="Qiwen" last="Yang">Qiwen Yang</name><name sortKey="Yang, Siyuan" sort="Yang, Siyuan" uniqKey="Yang S" first="Siyuan" last="Yang">Siyuan Yang</name><name sortKey="Zhang, Lulu" sort="Zhang, Lulu" uniqKey="Zhang L" first="Lulu" last="Zhang">Lulu Zhang</name><name sortKey="Zhu, Huadong" sort="Zhu, Huadong" uniqKey="Zhu H" first="Huadong" last="Zhu">Huadong Zhu</name></country><country name="États-Unis"><region name="Connecticut"><name sortKey="Dela Cruz, Charles S" sort="Dela Cruz, Charles S" uniqKey="Dela Cruz C" first="Charles S" last="Dela Cruz">Charles S. Dela Cruz</name></region><name sortKey="Sharma, Lokesh" sort="Sharma, Lokesh" uniqKey="Sharma L" first="Lokesh" last="Sharma">Lokesh Sharma</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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